Our natural optimal human diet is a diet that our hominin ancestors were eating for the last 30 million years, not anatomically modern humans in the Stone age.

Milos Pokimica

Written By: Milos Pokimica

Medically Reviewed by: Dr. Xiùying Wáng, M.D.

Updated August 4, 2023
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Milos Pokimica is a doctor of natural medicine, clinical nutritionist, medical health and nutrition writer, and nutritional science advisor. Author of the book series Go Vegan? Review of Science, he also operates the natural health website GoVeganWay.com

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GoVeganWay.com brings you reviews of the latest nutrition and health-related research. The information provided represents the personal opinion of the author and is not intended nor implied to be a substitute for professional medical advice, diagnosis, or treatment.  The information provided is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider.
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NEVER APPLY ANY LIFESTYLE CHANGES OR ANY CHANGES AT ALL AS A CONSEQUENCE OF SOMETHING YOU HAVE READ IN GoVeganWay.com BEFORE CONSULTING LICENCED MEDICAL PRACTITIONER.
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Milos Pokimica is a doctor of natural medicine, clinical nutritionist, medical health and nutrition writer, and nutritional science advisor. Author of the book series Go Vegan? Review of Science, he also operates the natural health website GoVeganWay.com

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    PubMed, #vegan-diet
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      CONCLUSION: The German version of the LAKE score is a rapid, inexpensive and feasible tool for an initial PRAL evaluation in a clinical context, characterized by a good validity and reliability. Results suggest that the German LAKE score could be suitable as an estimate for an individual’s PRAL, and could also guide clinicians to make dietary recommendations and monitor PRAL-relevant changes in individual patients.

    • Biological versus Technical Reliability of Epigenetic Clocks and Implications for Disease Prognosis and Intervention Response
      on November 24, 2025

      DNA methylation-based aging biomarkers, or epigenetic clocks, are increasingly used to estimate biological age and predict health outcomes. Their translational utility, however, depends not only on predictive accuracy but also on reliability, the ability to provide consistent results across technical replicates and repeated biological measures. Here, we leveraged the TranslAGE platform to comprehensively evaluate the technical and biological reliability of 18 Epigenetic clocks, including…

    • Learning molecular fingerprints of foods to decode dietary intake
      on November 24, 2025

      Assessing dietary intake from biological samples provides critical objective insights into nutrition and health. We present a reference-based strategy using untargeted metabolomics to estimate relative dietary composition. The approach learns food-specific molecular ion features first – both annotated and unannotated – via supervised classification and discriminant analysis. These features then guide extraction of corresponding MS1 intensities from unknown samples, enabling proportional,…

    • Eating within planetary boundaries – a cross-country analysis of iodine provision from the EAT-Lancet diet
      on November 24, 2025

      The EAT-Lancet Commission’s 2019 reference diet promotes health and environmental sustainability through predominantly plant-based foods, raising concerns about micronutrient adequacy, particularly iodine. This study evaluated the iodine content of the EAT-Lancet diet across sixteen countries using national food composition data. Iodine intake was modelled under three scenarios: (1) strict adherence to specified food items; (2) inclusion of a broader range of foods within each group; and (3) […]

    • Vegetarian and Vegan Diets and the Risk of Hip Fracture in Adults: A Systematic Review and Meta-analysis
      on November 23, 2025

      CONCLUSION: These findings emphasize the importance of incorporating dietary patterns into strategies for promoting bone health, especially among individuals following plant-based diets. Healthcare providers should offer guidance to individuals adopting vegetarian or vegan diets to ensure adequate nutrient intake and support bone health.

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