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by Milos Pokimica ND

by Milos Pokimica ND

Learn About Nutrition

Minnesota starvation experiment- Why dieting makes us fat. The psychology of hunger.

"One of the first scientific studies on what hunger does to the mind was observed in a study remembered as the Minnesota Starvation Experiment"

One of the first scientific studies on what hunger does to the mind was observed in a study remembered as the Minnesota Starvation Experiment performed by the University of Minnesota back in 1944. The lead investigator was Ancel Keys who had two Ph.D.’s one from biology and one from psychology. Thirty-six men were selected that were healthy and had no eating disorders from hundreds that volunteered.

Minnesota starvation experiment was a study where the goal was to live on a diet of 1500 calories for six months. In the first 12 weeks, there was a 3200 calorie control period, and then a real experiment started. Now 1500 calories are far from real starvation. The American government wanted to understand what psychological and physiological effects are going to be on war-torn Europe with starvation and holocaust. There was no industrial or direct military interest in this. It was done as a defense interest project because no one has done anything similar in the past and there was a real concern about the behavior of people that have been exposed to terror and starvation. There was a concern that people that have been released from concentration camps and that have gone through starvation on the battlefront might pose a threat to society. Also, the government wanted to have a guide for rehabilitating those who were starving.

Men were housed in a basement in the Minnesota University Stadium in windowless rooms with a program of mental and physical exercises. Diet was strictly controlled, and they could not cheat because they were in some sense incarcerated for six months. The scientist initially didn’t think of this experiment as a behavioral experiment in terms of evolutional psychology. The experiment without their initial realization reconstructed the conditions of habitat that existed during the evolution of a human species. An environment of scarcity. Starvation and survival of the fittest. This was an environment that was similar to most of the human evolution and as such was more normal than our current environment. It was an environment in which our brain evolved and was designed to cope with. Normal conditions of our current abundance of food were in an essence unnatural. The behavior and hunger in the environment of scarcity with a high death rate were the groundwork for understanding what drives our instincts and how strong those instincts are.

On a calorie restriction of 1500 calories after some initial period subjects started to lose weight and by the end of the study, they lost a significant number of pounds. What was more important is that the experiment did show significant behavioral changes. Starvation did have psychological effects on them.

In the beginning, they started to be apathetic, irritated and they developed ritualized eating patterns. Putting water into potatoes to make them bigger. Holding the food in the mouth and chewing for an extended period. Licking the plates. Daydreams of food, chewing gum, smoking cigarettes until someone had 30 packs per day. Drinking a ton of water to fill their stomachs. Then they started to enjoy solitary activities and looked at food in a sexual manner. They had no regular sex drive and was only interested in what people ate. They developed an eating disorder mentality. They started to feel bad about themselves if they binge and felt guilt with food. What they considered normal weight before, during the study was considered to be overweight. When they look at their old pictures, they thought they have big stomachs and much more weight than what will in that situation for them to be normal human physique. They experienced confusion when they are hungry and also when they are not.

This is an extract from one of the volunteer’s diary:

“I am beginning to isolate myself from other subjects. We are developing all kinds of weird behaviors. Everyone seems to be losing their interpersonal skills and starvation is less than half over. One of them bit the other volunteers. Many tried to escape from the compound to eat grass from nearby gardens. Another became so deranged that he chopped three of his fingers off with an ax.”

Later the ax men stated that he was “messed up” and that he could not remember why or how he chopped his fingers, and he could not say that he did not do it on purpose. This is what a strict diet of 1500 calories did to this person in less than six months.

minnesota Starvation Experiment
Minnesota Starvation Experiment

In cases of hunger, human behavior was shifted to survival mode. Nothing was important except for food. They didn’t care about moral and social norms and didn’t care about sex. They have completely emerged into existentialism that any external input that didn’t have a direct effect on their survival was of less importance to them. Aggressive behavior was avoided only because there was no chance of escaping and because of legal consequences. They were locked in underground “prison” in the stadium and had very little chance of physical escaping. The scientist predicted this and were strict in subject selection. Before they were chosen to be part of the experiment subjects had to show an ability to get along well with others under trying circumstances and had to have an interest in relief work. They selected nice young men with a good moral compass that had no psychological disorders before the experiment.

What happened after the experiment is even more important. 

When they started to feed on their own wish there was something entirely unexpected. They rapidly put on weight but not only that. They gained more than what they had at the starting point. Dieting made them fatter. They experienced something called extreme hunger. They ate and ate and ate and ate and never felt satisfied. Most companies in the diet industry and medical care know about this.

Dieting can make you fatter. Fear of starvation is real. Psychophysical dependence on supernormal stimuli is real. Human beings are evolutionarily conditioned for extreme eating because of the scarcity in nature.

Minnesota starvation experiment in later years became a base for an understanding of human psychology. Most of the scientists that work for the food industry know about the Minnesota starvation experiment very well. It is a well-known fact from that period onward that dieting does not work. After the Minnesota starvation experiment, the term “yo-yo” dieting was coined. Everyone that sells diets and supplements, diet plans, and books, all of the scientists in the labs of big food companies know about this experiment. It was one of the ground-breaking experiments that build a foundation of nutritional science. Food companies, for example, will promote food that is supernormal stimuli (a combination of fat and sugar at the same meal) to the children knowing that once when the brain adapts to that stimulation they will be addicted for life.

The way that we are condition to behave is at number one avoidance of pain. When pain is avoided pleasure-seeking comes into play. Because of a self-preservation mechanism our brain works by “carrot and a stick” mechanism. Avoidance of pain is a foundation of individual behavior. Until the pain is removed the pleasure-seeking does not exist and is redundant. People can lose their entire identity and their entire self-controlling mechanisms when forced to be in a state of extreme hunger. We are not in charge.

Psychologists were well aware of this even before the Minnesota starvation experiment. But what was a real discovery is that the fear of starvation never, in reality, went away.

Today there is a wide range of clinical experiments that have been done. At the University of Gothenburg in recent years, there was a line of studies but in all cases the conclusion was similar. Ghrelin, “hunger hormone”, was found for example to directly effects the ventral tegmental area, the part of the brain that is a crucial component of the reward system. Ghrelin injections in rats also caused changes in dopamine-related genes and enzymes (controlling the reward and pleasure centers of the brain) and were also found to make rats more impulsive (1).

ghrelin and the brain
Ghrelin Receptor in Appetite and Food Intake Regulation (4)

Millions of years of evolution have conditioned our behavior and in a normal natural environment is an evolutionary protective mechanism. In our modern technology-driven environment without scarcity self-controlling mechanisms don’t really work.

I always like to give a comparison with drowning. If we want to commit suicide by holding our breath, for example, we will not be able to. Sooner or later our brain will override our behavior and will gasp for air. It detects pain and it is in a state of dying one way or the other so there is nothing to lose anyway. This is a reason people always drown and not suffocate. The same story is with food or water. People will overeat because they can. Any type of dieting will make things even worse in the long run. Even if we try to lose weight we are going to be in a constant struggle against our conditioning. And even if we do prevail, it is not possible to be in a state of hunger and enjoy life. Especially because now we are removed from our natural environment and we have supernormal stimuli everywhere. Even a normal feeling of hunger is something that we cannot take as a normal feeling anymore.

Related Posts

  1. binge eating
  2. Malta Venus 4500 b.c.
  3. Hunger
  4. bmi index
  5. supernormal stimuli

Sources:

Passages selected from a book: “Go Vegan? Review of Science: Part 1” [Milos Pokimica]

  1. The Stomach-Derived Hormone Ghrelin Increases Impulsive Behavior. doi: 10.1038/npp.2015.297
  2. They starved so that others be better fed: Remembering Ancel Keys and the Minnesota Experiment. J Nutr. 2005 Jun;135(6):1347-52.
  3. The biology of human starvation, (Vols. 1–2). Minneapolis, MN: University of Minnesota Press. Keys, A., Brozek, J., Henshel, A., Mickelson, O., & Taylor, H.L. (1950).
  4. From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation. DOI: 10.3390/ijms18020273 

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Are we omnivores, carnivores or herbivores? It’s important for animals to eat what they are physiologically and anatomically designed to eat, to improve the chances of survival and health. So, what are humans designed to eat? Dr. Sofia Pineda Ochoa discusses this often misunderstood topic.

The first part of the transcript is included below for reference, and the full transcript (which is too long to have here) is available on our website, along with sources and credits, at this link: http://meatyourfuture.com/2015/09/herbivores-carnivores/

[The following transcript is an approximation of the audio in  video. To hear the audio and see the accompanying visuals, please play the video.]

PARTIAL TRANSCRIPT:

Are humans herbivores, carnivores or omnivores? It’s very important for a given animal to eat what they are physiologically and anatomically designed to eat, to improve the chances of survival and health. So, what are humans designed to eat?

When looking at a species to determine what they are in terms of carnivore, omnivore or herbivore, we can look at their behavior or we can look at their biology. From a behavioral standpoint, humans behave as omnivores because we observe many humans in their behavior eating a wide variety of both animal and plant-based foods. Biologically, however, from a physiologic and anatomic standpoint, it’s a different story.

Dr. Williams C. Roberts from the National Institutes of Health and Baylor University — who is the editor-in-chief of the American Journal of Cardiology and one of the most prominent cardiologists in the world with over 1,500 publications in peer reviewed medical journals — summarized our answer very nicely. He wrote:

“Although most of us conduct our lives as omnivores, in that we eat flesh as well as vegetables and fruits, human beings have characteristics of herbivores, not carnivores. The appendages of carnivores are claws; those of herbivores are hands or hooves. The teeth of carnivores are sharp; those of herbivores are mainly flat (for grinding). The intestinal tract of carnivores is short (3 times body length); that of herbivores, long (12 times body length). Body cooling of carnivores is done by panting; herbivores, by sweating. Carnivores drink fluids by lapping; herbivores, by sipping. Carnivores produce their own vitamin C, whereas herbivores obtain it from their diet. Thus, humans have characteristics of herbivores, not carnivores.”

That’s right. Humans have characteristics of herbivores, not carnivores or omnivores — because omnivores, like bears and raccoons, actually retain most of the carnivorous characteristics, so that they are still able to digest and hunt their prey, and do so effectively.

[Remainder of transcript, along with sources and credits, available here: http://meatyourfuture.com/2015/09/herbivores-carnivores]

Are we omnivores, carnivores or herbivores? It’s important for animals to eat what they are physiologically and anatomically designed to eat, to improve the chances of survival and health. So, what are humans designed to eat? Dr. Sofia Pineda Ochoa discusses this often misunderstood topic.

The first part of the transcript is included below for reference, and the full transcript (which is too long to have here) is available on our website, along with sources and credits, at this link: http://meatyourfuture.com/2015/09/herbivores-carnivores/

[The following transcript is an approximation of the audio in video. To hear the audio and see the accompanying visuals, please play the video.]

PARTIAL TRANSCRIPT:

Are humans herbivores, carnivores or omnivores? It’s very important for a given animal to eat what they are physiologically and anatomically designed to eat, to improve the chances of survival and health. So, what are humans designed to eat?

When looking at a species to determine what they are in terms of carnivore, omnivore or herbivore, we can look at their behavior or we can look at their biology. From a behavioral standpoint, humans behave as omnivores because we observe many humans in their behavior eating a wide variety of both animal and plant-based foods. Biologically, however, from a physiologic and anatomic standpoint, it’s a different story.

Dr. Williams C. Roberts from the National Institutes of Health and Baylor University — who is the editor-in-chief of the American Journal of Cardiology and one of the most prominent cardiologists in the world with over 1,500 publications in peer reviewed medical journals — summarized our answer very nicely. He wrote:

“Although most of us conduct our lives as omnivores, in that we eat flesh as well as vegetables and fruits, human beings have characteristics of herbivores, not carnivores. The appendages of carnivores are claws; those of herbivores are hands or hooves. The teeth of carnivores are sharp; those of herbivores are mainly flat (for grinding). The intestinal tract of carnivores is short (3 times body length); that of herbivores, long (12 times body length). Body cooling of carnivores is done by panting; herbivores, by sweating. Carnivores drink fluids by lapping; herbivores, by sipping. Carnivores produce their own vitamin C, whereas herbivores obtain it from their diet. Thus, humans have characteristics of herbivores, not carnivores.”

That’s right. Humans have characteristics of herbivores, not carnivores or omnivores — because omnivores, like bears and raccoons, actually retain most of the carnivorous characteristics, so that they are still able to digest and hunt their prey, and do so effectively.

[Remainder of transcript, along with sources and credits, available here: http://meatyourfuture.com/2015/09/herbivores-carnivores]

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Are humans omnivores, carnivores or herbivores?

GoVeganWay 351K views September 4, 2021 12:32 am

How much is a human life worth? An innovative cancer therapy promises to save lives. But it is extremely expensive. Will the insurance companies pay for it? What is the manufacturer's return on investment? And do lobbyists drive up prices?

In 2018, the Kymriah gene therapy was approved in Europe. Immune cells are taken from the patient, genetically reprogrammed into cancer killer cells and returned to the patient as an infusion. The results of the Kymriah study only cover a period of 18 months. In 40 percent of patients, lymph gland cancer does not return during this time. It is not clear whether Kymriah has a long-term effect. The Swiss pharmaceutical company Novartis offers the new therapy - it costs 370,000 Swiss francs per patient. Health insurance companies are not usually prepared to pay that much and are complaining about a lack of transparency. 

But the killer cells were not invented in the Novartis laboratories, but at a US university. When Professor Carl June started his research almost 30 years ago, no pharmaceutical company was interested. It was only thanks to funding from tax money and donations that he was able to develop Kymriah at all. After a story went around the world about a girl with leukemia whose cancer disappeared thanks to Kymriah, the pharmaceutical company contacted Novartis and secured exclusive marketing rights. To launch Kymriah on the market, Novartis funded the necessary clinical trials. It's not an isolated incident: Over 60% of newly approved medicines in the US are developed by small biotech companies or universities. Pharmaceutical companies today frequently act as capital providers, cooperating with universities or buying up biotech companies. 

A paradigm shift has taken place in the pharmaceutical industry: Whereas high drug prices used to be justified by research costs, the industry is now using the value of gained lifetime to argue its case. 

 -------------------------------------------------------------------

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How much is a human life worth? An innovative cancer therapy promises to save lives. But it is extremely expensive. Will the insurance companies pay for it? What is the manufacturer's return on investment? And do lobbyists drive up prices?

In 2018, the Kymriah gene therapy was approved in Europe. Immune cells are taken from the patient, genetically reprogrammed into cancer killer cells and returned to the patient as an infusion. The results of the Kymriah study only cover a period of 18 months. In 40 percent of patients, lymph gland cancer does not return during this time. It is not clear whether Kymriah has a long-term effect. The Swiss pharmaceutical company Novartis offers the new therapy - it costs 370,000 Swiss francs per patient. Health insurance companies are not usually prepared to pay that much and are complaining about a lack of transparency.

But the killer cells were not invented in the Novartis laboratories, but at a US university. When Professor Carl June started his research almost 30 years ago, no pharmaceutical company was interested. It was only thanks to funding from tax money and donations that he was able to develop Kymriah at all. After a story went around the world about a girl with leukemia whose cancer disappeared thanks to Kymriah, the pharmaceutical company contacted Novartis and secured exclusive marketing rights. To launch Kymriah on the market, Novartis funded the necessary clinical trials. It's not an isolated incident: Over 60% of newly approved medicines in the US are developed by small biotech companies or universities. Pharmaceutical companies today frequently act as capital providers, cooperating with universities or buying up biotech companies.

A paradigm shift has taken place in the pharmaceutical industry: Whereas high drug prices used to be justified by research costs, the industry is now using the value of gained lifetime to argue its case.

-------------------------------------------------------------------

DW Documentary gives you knowledge beyond the headlines. Watch high-class documentaries from German broadcasters and international production companies. Meet intriguing people, travel to distant lands, get a look behind the complexities of daily life and build a deeper understanding of current affairs and global events. Subscribe and explore the world around you with DW Documentary.

Subscribe to:
DW Documentary: https://www.youtube.com/channel/UCW39zufHfsuGgpLviKh297Q?sub_confirmation=1#

DW Documental (Spanish): https://www.youtube.com/dwdocumental
DW Documentary وثائقية دي دبليو: (Arabic): https://www.youtube.com/dwdocarabia

For more visit:
http://www.dw.com/en/tv/docfilm/s-3610
Instagram:
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Facebook:
https://www.facebook.com/dw.stories

DW netiquette policy: https://p.dw.com/p/MF1G

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The power of the pharmaceutical companies | DW Documentary

GoVeganWay 648.6K views September 4, 2021 12:24 am

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