養殖魚 - 「セスプール」の楽園

A next-generation drug tested in yeast was found to extend lifespan and slow aging by influencing a major growth-control pathway. Researchers also uncovered an unexpected role for agmatinases, enzymes that help keep this pathway in balance. Diet and gut microbes may affect aging more than expected because they produce the metabolites involved.

Regular consumption of polyphenol-rich foods like tea, coffee, berries, nuts, and whole grains may significantly support long-term heart health. A decade-long study of more than 3,100 adults found that those who consistently ate polyphenol-packed diets had healthier blood pressure and cholesterol levels, as well as lower predicted cardiovascular risk.

A large study found that people with impaired kidneys tend to have higher Alzheimer’s biomarkers, yet they don’t face a higher overall risk of dementia. For those who already have elevated biomarkers, kidney problems may speed up when symptoms appear. The findings show that kidney health can change how Alzheimer’s blood tests are read. Doctors may need to consider both organs to get a clearer picture.

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore injured tissue. The discovery came from studying tiny molecular messages released by heart cells that naturally support healing after injury. By identifying and recreating the most powerful of these messages, the team developed a synthetic RNA molecule that boosts the body’s DNA-repair system, reduces scarring, and may improve recovery after heart attacks and other […]

Researchers found that people with anxiety disorders consistently show lower choline levels in key brain regions that regulate thinking and emotions. This biochemical difference may help explain why the brain reacts more intensely to stress in anxiety conditions. Scientists believe nutrition could play a role in restoring balance, though more research is needed. Many Americans already fall short of recommended choline intake, making diet a potential area of interest.

Researchers studying people with major psychiatric disorders found that drinking up to four cups of coffee a day is associated with longer telomeres. This suggests a potential slowing of biological aging by about five years. However, drinking five or more cups showed no benefit and may even contribute to cellular damage. Coffee’s antioxidant and anti-inflammatory properties may help explain the effect.

A low-dose mix of zinc, serine, and branched-chain amino acids boosted neural function and social behavior in autism mouse models. The combination restored more typical synaptic protein patterns and reduced excessive amygdala activity. Individual supplements had no effect, showing that the nutrients must work together. The findings point toward a promising multi-nutrient strategy for influencing brain circuits involved in autism.