マクガバン報告書 - 特別な関心と科学の抑圧

Scientists have uncovered promising clues that compounds found in Aloe vera could play a role in fighting Alzheimer’s disease. Using advanced computer modeling, researchers discovered that beta-sitosterol—a natural plant compound—strongly interacts with two key enzymes involved in memory loss and cognitive decline. The compound showed stability, strong binding, and favorable safety indicators, making it a standout candidate for future drug development.

Scientists have identified a promising new compound, Mic-628, that can reliably shift the body’s internal clock forward—something that’s notoriously hard to do. By targeting a key clock-control protein, Mic-628 jump-starts the gene that sets daily rhythms, synchronizing both the brain’s master clock and clocks throughout the body. In mice experiencing simulated jet lag, a single dose cut recovery time nearly in half.

What a mother eats during pregnancy may quietly shape her child’s liver health years down the road—but new research suggests there may be a way to tip the odds back in a healthier direction. Scientists found that a natural compound made by healthy gut bacteria dramatically reduced fatty liver disease in the offspring of mice whose mothers ate a high-fat, high-sugar diet. The compound, called indole, appeared to protect the liver, improve blood sugar, limit weight gain, and even reshape the […]

New research suggests the astringent sensation caused by flavanols could act as a direct signal to the brain, triggering effects similar to a mild workout for the nervous system. In mouse experiments, flavanol intake boosted activity, curiosity, learning, and memory—despite these compounds barely entering the bloodstream. The key appears to be sensory stimulation: the taste itself activates brain pathways linked to attention, motivation, and stress response, lighting up regions involved in […]

New simulations reveal that both H1N1 and COVID-19 spread across U.S. cities in a matter of weeks, often before officials realized what was happening. Major travel hubs helped drive rapid nationwide transmission, with air travel playing a bigger role than daily commuting. Unpredictable transmission patterns made real-time forecasting especially difficult. The study highlights why early detection systems are critical for slowing future pandemics.

A major study suggests menopause is linked to changes in brain structure, mental health, and sleep. Brain scans revealed grey matter loss in areas tied to memory and emotional regulation, while many women reported increased anxiety, depression, and fatigue. Hormone therapy did not reverse these effects, though it may slow age-related declines in reaction speed. Researchers say menopause could represent an important turning point for brain health.

For decades, Americans were surrounded by lead from car exhaust, factories, paint, and even drinking water, often without realizing the damage it caused. By analyzing hair samples preserved across generations, scientists uncovered a striking record of how exposure soared before environmental rules and then collapsed after leaded gasoline and other sources were phased out.